Levosulpiride+Pantoprazole is used in the treatment of gastroesophageal reflux disease (acid reflux). Levosulpiride + Pantoprazole is a combination of two medicines: Levosulpiride and Pantoprazole. Levosulpiride is a prokinetic which works by increasing the release of acetylcholine (a chemical messenger). LEVOSULPIRIDE+PANTOPRAZOLE is a combination of two drugs, namely: Pantoprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Pantoprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby prevents backflow of food and acid into the mouth. Together, LEVOSULPIRIDE+PANTOPRAZOLE helps in preventing acid reflux, thereby provides relief from acidity and heartburn.